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Palliative Medicine
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How do terminally ill patients at home take their medication?

Giovambattista Zeppetella

Compliance with prescribed medication was assessed in 111 terminally ill patients referred to a community palliative care team using semistructured interviews and pill counting. One-hundred-and-six patients were prescribed a total of 597 drugs; of these patients, 64 (60%) were noncompliant.

Thirty-five patients (33%) took less medication than prescribed, usually due to experiencing, or anxieties about, adverse events; the commonest drugs involved were analgesics. Seventeen patients (16%) took additional medication, usually purchased over the counter in response to inadequate symptom control or to adverse events from other drugs; the most common preparations were vitamins and analgesics. Twelve patients (11%) both took less medication than prescribed and also purchased medication over the counter.

Most patients (90%) had two or more prescribers; patients who saw their general practitioners as their main prescriber were more likely to adhere to their prescribed medication. Patients who omitted and/or reduced their medication were more likely to see the hospital as their main prescriber. Drugs prescribed four times daily were most likely to be omitted and/or reduced.

Key Words: home nursing • neoplasms • patient compliance • prescriptions, drug • terminally ill

Palliative Medicine, Vol. 13, No. 6, 469-475 (1999)
DOI: 10.1191/026921699675653923


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P. Armes and J. Addington-Hall
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Palliative Medicine, October 1, 2003; 17(7): 608 - 615.
[Abstract] [PDF]