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Palliative Medicine
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Carbamazepine-responsive paroxysmal nausea and vomiting in a patient with meningeal carcinomatosis

Imke Strohscheer

Section of Palliative Care, Medical University, Graz

Gian Domenico Borasio

Interdisciplinary Center for Palliative Medicine, Ludwig-Maximilians-University, Munich

In neurology, paroxysmal syndromes are well-known, eg, as manifestations of multiple sclerosis. We report a patient with meningeal carcinomatosis, who presented with therapyrefractory nausea and vomiting. The clinical suspicion of a paroxysmal syndrome prompted a trial of carbamazepine, which resulted in complete cessation of the symptoms. In cancer patients with central nervous system (CNS) involvement and therapy-refractory symptoms with sudden onset, carbamazepine treatment should be considered.

Palliative Medicine, Vol. 20, No. 5, 549-550 (2006)
DOI: 10.1191/0269216306pm1161xx
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