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The misuse/abuse of antihistamine antiemetic medication (cyclizine) by cancer patients

Woking Hospice, Woking, Surrey; Department of Palliative Medicine, Royal Marsden NHS Foundation Trust, Sutton, Surrey

A Davies

Department of Palliative Medicine, Royal Marsden NHS Foundation Trust, Sutton, Surrey andrew.davies{at}rmh.nhs.uk

Cyclizine is an antihistamine, which is frequently used to manage nausea and vomiting in cancer patients. Antihistamines can be drugs of misuse/abuse, and the article describes four cancer patients who developed such problems after receiving parenteral cyclizine within the inpatient unit of a cancer centre. The article also briefly reviews the literature on the misuse/abuse of cyclizine and other antihistamines.

Key Words: cyclizine • neoplasms • substance-related disorders

This version was published on October 1, 2008

Palliative Medicine, Vol. 22, No. 7, 869-871 (2008)
DOI: 10.1177/0269216308094337


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