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Palliative Medicine
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What's this?

Can ketamine prescribed for pain cause damage to the urinary tract?

TM Storr

Eden Valley Hospice, Carlisle, Cumbria, UK, teresa.storr{at}cumbriapct.nhs.uk

R. Quibell

Royal Victoria Infirmary, Newcastle upon Tyne

Presentation of three palliative care patients who were given ketamine as an analgesic and subsequently developed significant and debilitating urological symptoms. In one patient there was resolution of symptoms following cessation of ketamine, but some symptoms persisted until death in the other two. Possible mechanisms for damage to the urothelium by ketamine are suggested.

Key Words: analgesia • cystitis • dysuria • haematuria • ketamine • palliative

This version was published on October 1, 2009

Palliative Medicine, Vol. 23, No. 7, 670-672 (2009)
DOI: 10.1177/0269216309106828
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