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Palliative Medicine
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Effect of epidural morphine on various kinds of cancer pain

Ivan E Kiss

Department of Anaesthesiology, University Clinic of Freiburg

Bruno Simini

Department of Anaesthesiology, University Clinic of Freiburg

Johannes W May

Department of Neurosurgery, University Clinic of Freiburg, Freiburg

Thirty cancer patients with intractable pain were examined before and after five days of epidural opiate administration. The pain measurement was carried out with the German version of the McGill Pain Questionnaire. The patients with bone pain - the largest group - responded very well to the therapy. The spinal analgesia was less effective in patients whose complaints were mainly caused by visceral tumour growth or by the distension of pain-sensitive structures. The poorest results were seen in patients with predominantly nerve lesions and without bone involvement. However, a significant pain relief could be achieved in all patients due to the usually widespread sources of cancer pain.

Key Words: analgesia • epidural space • intractable pain • morphine • neoplasms • palliative treatment

Palliative Medicine, Vol. 3, No. 3, 217-221 (1989)
DOI: 10.1177/026921638900300309
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This article has been cited by other articles:


Home page
 Palliat MedHome page
D. Gorman
Review article : Opioid analgesics in the management of pain in patients with cancer: an update
Palliative Medicine, October 1, 1991; 5(4): 277 - 294.
[Abstract] [PDF]

Home page
 Palliat MedHome page
S. Ottesen, M. Minton, and R. G. Twycross
The use of epidural morphine at a palliative care centre
Palliative Medicine, April 1, 1990; 4(2): 117 - 122.
[Abstract] [PDF]