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Palliative Medicine
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Review article : Depression and the use of antidepressants in patients with cancer

Mary Cody

St Bartholomew's and Homerton Hospitals, London

Depressive disorders are common sequelae of cancer and its treatment. Fortunately, most of them are transient and respond to information, adequate explanation and emotional support from those involved in patient care. This article concentrates on the less common but more severe depressive disorders which require pharmacological strategies in addition to psychosocial interventions. Guidelines are suggested for identifying depressive disorders and the importance of ruling out potentially reversible organic pathology which may be responsible for the mood disturbance is also emphasized. Estimates of the prevalence of depressive disorders among cancer patients are provided and practical advice is offered on the choice of antidepressant, dosage and side-effects.

Key Words: antidepressant agents • depression • neoplasms • palliative treatment.

Palliative Medicine, Vol. 4, No. 4, 271-278 (1990)
DOI: 10.1177/026921639000400404
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This article has been cited by other articles:


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H A M. Meyer, C. Sinnott, and P. T Seed
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Palliative Medicine, October 1, 2003; 17(7): 596 - 603.
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P. Grzybowska and I. Finlay
The incidence of suicide in palliative care patients
Palliative Medicine, July 1, 1997; 11(4): 313 - 316.
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D. Power, S. Kelly, J. Gilsenan, M. Kearney, D. O'Mahony, J. B. Walsh, and D. Coakley
Suitable screening tests for cognitive impairment and depression in the terminally ill- a prospective prevalence study
Palliative Medicine, July 1, 1993; 7(3): 213 - 218.
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