Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Palliative Medicine
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by McDonald, P.
Right arrow Articles by Stuart-Harris, R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by McDonald, P.
Right arrow Articles by Stuart-Harris, R.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Regular subcutaneous bolus morphine via an indwelling cannula for pain from advanced cancer

P. McDonald

Palliative Care Unit, Parramatta Hospital

P. Graham

Department of Radiation Oncology, Westmead Hospital

M. Clayton

St Joseph's Hospital, Auburn

A. Buhagiar

Palliative Care Unit, Westmead Hospital

R. Stuart-Harris

Medical Oncology and Palliative Care Unit, Westmead Hospital, Australia

The analgesia and toxicity of regular four-hourly subcutaneous bolus morphine were assessed prospectively in 164 patients with pain from advanced cancer; each had received oral morphine for a minimum of 48 hours. World Health Organization (WHO) scores for pain, nausea and vomiting, and drowsiness taken at the time of change to subcutaneous bolus morphine and 48 hours later indicated that subcutaneous morphine provided significantly better analgesia than similar doses of oral morphine (p<0.001) and was associated with significantly less nausea and vomiting (p < 0.005). Scores for drowsiness were similar for both forms of morphine. Minor erythema or thickening at the injection site was noted in 86 patients (52%), but more severe local reactions occurred in seven patients (4%). Twenty-five patients (15%) were discharged home on subcutaneous bolus morphine given by themselves or relatives. Regular four-hourly subcutaneous bolus morphine is an effective and well tolerated method of parenteral morphine administration.

Key Words: analgesia • drug effects • morphine • subcutaneous injections

Palliative Medicine, Vol. 5, No. 4, 323-329 (1991)
DOI: 10.1177/026921639100500408
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Palliat MedHome page
J. Ingham and N. Cooney
Pneumothorax following insertion of subcutaneous needle
Palliative Medicine, October 1, 1992; 6(4): 343 - 344.
[Abstract] [PDF]