Palliative Medicine

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ripamonti, C.
Right arrow Articles by Bruera, E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Ripamonti, C.
Right arrow Articles by Bruera, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Palliative Medicine, Vol. 6, No. 2, 98-104 (1992)
DOI: 10.1177/026921639200600203

Reviews

Review articles : Transdermal and inhalatory routes of opioid administration: the potential application in cancer pain

Carla Ripamonti

Division of Palliative Care, National Cancer Institute, Milan, Italy

Eduardo Bruera

Palliative Care Program, Edmonton General Hospital, Edmonton, Alberta

The aim of this paper is a review of the data in the literature on the transdermal and inhalatory routes of opioid administration. The majority of the published experience is based on the use of transdermal and inhalatory opioids for the management of postoperative pain. Pharmacokinetic data suggest that transdermal fentanyl is well absorbed although there is a considerable delay in reaching steady state plasma level and also a slowly declining plasma concentration after removal of the transdermal patch. Clinical experience suggests that it is well-tolerated. There is very limited knowledge about the absorption and pharmacokinetics of morphine when given by the inhalatory route. A better understanding of the absorption and pharmacokinetics of different nebulized opioids is needed before reliable clinical trials can be designed on these drugs.

Key Words: cutaneous administration • drug administration • inhalation administration • opioids • pain • palliative treatment


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 AM J HOSP PALLIAT CAREHome page
R. W. Williams
Letters
American Journal of Hospice and Palliative Medicine, May 1, 1992; 9(3): 4 - 4.
[PDF]