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Palliative Medicine
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0269216309102520v1
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Article

Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup

S Dorman1*, C Jolley2, A Abernethy3, D Currow4, M Johnson5, M Farquhar6, G Griffiths7, T Peel8, S Moosavi9, A Byrne10, A Wilcock11, L Alloway12, C Bausewein13, I Higginson13, and S Booth14

1 Poole Hospital NHS Foundation Trust, Longfleet Road, Poole
2 King's College London, Division of Asthma, Allergy and Lung Biology, Denmark Hill, London
3 Division of Medical Oncology, Department of Medicine, Duke University Medical Center, United States
4 Department of Palliative and Supportive Services, Flinders University, Adelaide, Australia
5 University of Hull and Honorary Consultant to St Catherine's Hospice, Scarborough
6 General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge
7 Wales Cancer Trials Unit, Cardiff
8 North Tyneside General Hospital, Rake Lane, North Shields, Tyne & Wear
9 Airways Disease, Faculty of Medicine, National Heart and Lung Institute, Imperial College London
10 Marie Curie Centre, Bridgeman Road, Penarth, Vale of Glamorgan and Wales Cancer Trials Unit, Cardiff
11 Hayward House Macmillan Specialist Palliative Cancer Care Unit, Nottingham University Hospitals NHS Trust, City Hospital Campus, Hucknall Road, Nottingham
12 North Hampshire Palliative Care Service, Basingstoke
13 King's College London, London
14 Cambridge University Hospitals NHS Foundation Trust, Cambridge

* To whom correspondence should be addressed.


  Abstract

Breathlessness is common in advanced disease and can have a devastating impact on patients and carers. Research on the management of breathlessness is challenging. There are relatively few studies, and many studies are limited by inadequate power or design. This paper represents a consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup. The aims of this paper are to facilitate the design of adequately powered multi-centre interventional studies in breathlessness, to suggest a standardised, rational approach to breathlessness research and to aid future ‘between study' comparisons. Discussion of the physiology of breathlessness is included.

Key Words: breathlessness, dyspnoea, measurement, methodology, palliative care, research design

First published on February 27, 2009, doi:10.1177/0269216309102520

Palliative Medicine 2009;23:213.

A more recent version of this article appeared on April 1, 2009

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